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Japan issued the revision of the Order of Enforcement of Act on the Regulation of Manufacture and Evaluation of Chemical Substances.

Perfluorohexane sulfonic acid (PFHxS) is a highly surface-active perfluorinated compound with chemical properties similar to perfluorooctane sulfonic acid (PFOS). Following the ban on PFOS by the Stockholm Convention in 2009, PFHxS has been widely used as a substitute in various products. However, PFHxS is persistent in the environment, capable of long-range transport, and may cause developmental toxicity, neurotoxicity, hepatotoxicity, and reproductive toxicity. At the 10th Conference of the Parties to the Stockholm Convention (SC COP-10), PFHxS, its salts, and related compounds were listed in Annex A of the Convention for elimination, with no exemptions allowed.

Recently, Japan has detected sodium aluminate dioxide (CAS No.: 1302-42-7) in some imported products containing sodium aluminate (CAS number: 11138-49-1). In accordance with the announcement of the Ministry of Health, Labour and Welfare (MHLW), sodium aluminate dioxide was classified as deleterious substance under the Poisonous and Deleterious Substances Control Law (PDSCL) on July 1, 2018.